Evaluation of the diagnostic utility of fiberoptic bronchoscopy for smear-negative pulmonary tuberculosis in routine clinical practice

Alonso Soto; Daniela Salazar; Vilma Acurio; Patricia Segura; Patrick Van der Stuyft

doi:10.1590/s1806-37132012000600011

Evaluation of the diagnostic utility of fiberoptic bronchoscopy for smear-negative pulmonary tuberculosis in routine clinical practice

Alonso Soto
, Daniela Salazar
, Vilma Acurio
, Patricia Segura
, Patrick Van der Stuyft

Institute of Tropical Medicine
Hospital Nacional Hipolito Unanue
Universidad Peruana Cayetano Heredia
Ghent University

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

We evaluated the diagnostic yield of fiberoptic bronchoscopy for the diagnosis of smear-negative pulmonary tuberculosis in patients treated at a referral hospital in Lima, Peru. Of the 611 patients who underwent the procedure, 140 (23%) were diagnosed with tuberculosis based on the analysis of BAL samples. Being young and being male were significantly associated with positive cultures. In addition, 287 patients underwent post-bronchoscopic sputum smear testing for AFB, the results of which increased the diagnostic yield by 22% over that obtained through the analysis of BAL samples alone. We concluDe that the analysis of BAL samples and post-bronchoscopic sputum samples provides a high diagnostic yield in smear-negative patients suspected of having pulmonary tuberculosis.

Original language	English
Pages (from-to)	757-760
Number of pages	4
Journal	Jornal Brasileiro de Pneumologia
Volume	38
Issue number	6
DOIs	https://doi.org/10.1590/s1806-37132012000600011
State	Published - 2012
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Bronchoscopy
Pulmonary/diagnosis
Sputum
Tuberculosis

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10.1590/s1806-37132012000600011

Cite this

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title = "Evaluation of the diagnostic utility of fiberoptic bronchoscopy for smear-negative pulmonary tuberculosis in routine clinical practice",

abstract = "We evaluated the diagnostic yield of fiberoptic bronchoscopy for the diagnosis of smear-negative pulmonary tuberculosis in patients treated at a referral hospital in Lima, Peru. Of the 611 patients who underwent the procedure, 140 (23\%) were diagnosed with tuberculosis based on the analysis of BAL samples. Being young and being male were significantly associated with positive cultures. In addition, 287 patients underwent post-bronchoscopic sputum smear testing for AFB, the results of which increased the diagnostic yield by 22\% over that obtained through the analysis of BAL samples alone. We concluDe that the analysis of BAL samples and post-bronchoscopic sputum samples provides a high diagnostic yield in smear-negative patients suspected of having pulmonary tuberculosis.",

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AU - Soto, Alonso

AU - Salazar, Daniela

AU - Acurio, Vilma

AU - Segura, Patricia

AU - Van der Stuyft, Patrick

PY - 2012

Y1 - 2012

N2 - We evaluated the diagnostic yield of fiberoptic bronchoscopy for the diagnosis of smear-negative pulmonary tuberculosis in patients treated at a referral hospital in Lima, Peru. Of the 611 patients who underwent the procedure, 140 (23%) were diagnosed with tuberculosis based on the analysis of BAL samples. Being young and being male were significantly associated with positive cultures. In addition, 287 patients underwent post-bronchoscopic sputum smear testing for AFB, the results of which increased the diagnostic yield by 22% over that obtained through the analysis of BAL samples alone. We concluDe that the analysis of BAL samples and post-bronchoscopic sputum samples provides a high diagnostic yield in smear-negative patients suspected of having pulmonary tuberculosis.

AB - We evaluated the diagnostic yield of fiberoptic bronchoscopy for the diagnosis of smear-negative pulmonary tuberculosis in patients treated at a referral hospital in Lima, Peru. Of the 611 patients who underwent the procedure, 140 (23%) were diagnosed with tuberculosis based on the analysis of BAL samples. Being young and being male were significantly associated with positive cultures. In addition, 287 patients underwent post-bronchoscopic sputum smear testing for AFB, the results of which increased the diagnostic yield by 22% over that obtained through the analysis of BAL samples alone. We concluDe that the analysis of BAL samples and post-bronchoscopic sputum samples provides a high diagnostic yield in smear-negative patients suspected of having pulmonary tuberculosis.

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KW - Pulmonary/diagnosis

KW - Sputum

KW - Tuberculosis

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DO - 10.1590/s1806-37132012000600011

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SN - 1806-3713

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SP - 757

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JO - Jornal Brasileiro de Pneumologia

JF - Jornal Brasileiro de Pneumologia

IS - 6

ER -

Evaluation of the diagnostic utility of fiberoptic bronchoscopy for smear-negative pulmonary tuberculosis in routine clinical practice

Abstract

UN SDGs

Keywords

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