Frequency and coinfection between genotypes of human papillomavirus in a population of asymptomatic women in northern Peru

Luis Ponce-Benavente; Patricia Rejas-Pinelo; Miguel Angel Aguilar-Luis; Carlos Palomares-Reyes; Lorena Becerra-Goicochea; Luis Pinillos-Vilca; Wilmer Silva-Caso; Luis E. Costa; Pablo Weilg; Juan Alvitrez-Arana; Jorge Bazán-Mayra; Juana Del Valle-Mendoza

doi:10.1186/s13104-018-3644-7

Frequency and coinfection between genotypes of human papillomavirus in a population of asymptomatic women in northern Peru

Luis Ponce-Benavente
, Patricia Rejas-Pinelo
, Miguel Angel Aguilar-Luis
, Carlos Palomares-Reyes
, Lorena Becerra-Goicochea
, Luis Pinillos-Vilca
, Wilmer Silva-Caso
, Luis E. Costa
, Pablo Weilg
, Juan Alvitrez-Arana
, Jorge Bazán-Mayra
, Juana Del Valle-Mendoza

Universidad Peruana de Ciencias Aplicadas
Instituto de Investigación Nutricional
Instituto de Investigación de Enfermedades Infecciosas
Hospital Regional Docente de Cajamarca
Universidad Viña del Mar
Dirección Regional de Salud de Cajamarca (DIRESA-Cajamarca)

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Objective: Describe the prevalence of HPV genotypes via PCR and DNA sequencing in 397 women who attended to the gynecological outpatient center in the Hospital Regional Docente de Cajamarca from March to September 2017. Results: A positive PCR result for HPV was observed in 121 cervical samples. A high-risk genotype was found in 63.6% (77/121) of patients, a probably oncogenic type in 23.1% (28/121) and a low-risk type in 7.4%. Among the high-risk genotypes, HPV-31 was the most common one present in 20% (21/77), followed by HPV-16 in 11.4% (12/77). Coinfections between two or more genotypes were observed in 12 cases.

Original language	English
Article number	530
Journal	BMC Research Notes
Volume	11
Issue number	1
DOIs	https://doi.org/10.1186/s13104-018-3644-7
State	Published - 31 Jul 2018

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Cervical cancer
HPV
PCR
Peru

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10.1186/s13104-018-3644-7

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Ponce-Benavente, L., Rejas-Pinelo, P., Aguilar-Luis, M. A., Palomares-Reyes, C., Becerra-Goicochea, L., Pinillos-Vilca, L., Silva-Caso, W., Costa, L. E., Weilg, P., Alvitrez-Arana, J., Bazán-Mayra, J., & Del Valle-Mendoza, J. (2018). Frequency and coinfection between genotypes of human papillomavirus in a population of asymptomatic women in northern Peru. BMC Research Notes, 11(1), Article 530. https://doi.org/10.1186/s13104-018-3644-7

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title = "Frequency and coinfection between genotypes of human papillomavirus in a population of asymptomatic women in northern Peru",

abstract = "Objective: Describe the prevalence of HPV genotypes via PCR and DNA sequencing in 397 women who attended to the gynecological outpatient center in the Hospital Regional Docente de Cajamarca from March to September 2017. Results: A positive PCR result for HPV was observed in 121 cervical samples. A high-risk genotype was found in 63.6\% (77/121) of patients, a probably oncogenic type in 23.1\% (28/121) and a low-risk type in 7.4\%. Among the high-risk genotypes, HPV-31 was the most common one present in 20\% (21/77), followed by HPV-16 in 11.4\% (12/77). Coinfections between two or more genotypes were observed in 12 cases.",

keywords = "Cervical cancer, HPV, PCR, Peru",

author = "Luis Ponce-Benavente and Patricia Rejas-Pinelo and Aguilar-Luis, \{Miguel Angel\} and Carlos Palomares-Reyes and Lorena Becerra-Goicochea and Luis Pinillos-Vilca and Wilmer Silva-Caso and Costa, \{Luis E.\} and Pablo Weilg and Juan Alvitrez-Arana and Jorge Baz{\'a}n-Mayra and \{Del Valle-Mendoza\}, Juana",

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Ponce-Benavente, L, Rejas-Pinelo, P, Aguilar-Luis, MA, Palomares-Reyes, C, Becerra-Goicochea, L, Pinillos-Vilca, L, Silva-Caso, W, Costa, LE, Weilg, P, Alvitrez-Arana, J, Bazán-Mayra, J & Del Valle-Mendoza, J 2018, 'Frequency and coinfection between genotypes of human papillomavirus in a population of asymptomatic women in northern Peru', BMC Research Notes, vol. 11, no. 1, 530. https://doi.org/10.1186/s13104-018-3644-7

TY - JOUR

T1 - Frequency and coinfection between genotypes of human papillomavirus in a population of asymptomatic women in northern Peru

AU - Ponce-Benavente, Luis

AU - Rejas-Pinelo, Patricia

AU - Aguilar-Luis, Miguel Angel

AU - Palomares-Reyes, Carlos

AU - Becerra-Goicochea, Lorena

AU - Pinillos-Vilca, Luis

AU - Silva-Caso, Wilmer

AU - Costa, Luis E.

AU - Weilg, Pablo

AU - Alvitrez-Arana, Juan

AU - Bazán-Mayra, Jorge

AU - Del Valle-Mendoza, Juana

PY - 2018/7/31

Y1 - 2018/7/31

N2 - Objective: Describe the prevalence of HPV genotypes via PCR and DNA sequencing in 397 women who attended to the gynecological outpatient center in the Hospital Regional Docente de Cajamarca from March to September 2017. Results: A positive PCR result for HPV was observed in 121 cervical samples. A high-risk genotype was found in 63.6% (77/121) of patients, a probably oncogenic type in 23.1% (28/121) and a low-risk type in 7.4%. Among the high-risk genotypes, HPV-31 was the most common one present in 20% (21/77), followed by HPV-16 in 11.4% (12/77). Coinfections between two or more genotypes were observed in 12 cases.

AB - Objective: Describe the prevalence of HPV genotypes via PCR and DNA sequencing in 397 women who attended to the gynecological outpatient center in the Hospital Regional Docente de Cajamarca from March to September 2017. Results: A positive PCR result for HPV was observed in 121 cervical samples. A high-risk genotype was found in 63.6% (77/121) of patients, a probably oncogenic type in 23.1% (28/121) and a low-risk type in 7.4%. Among the high-risk genotypes, HPV-31 was the most common one present in 20% (21/77), followed by HPV-16 in 11.4% (12/77). Coinfections between two or more genotypes were observed in 12 cases.

KW - Cervical cancer

KW - HPV

KW - PCR

KW - Peru

UR - https://www.scopus.com/pages/publications/85051262296

U2 - 10.1186/s13104-018-3644-7

DO - 10.1186/s13104-018-3644-7

M3 - Artículo

C2 - 30064521

AN - SCOPUS:85051262296

SN - 1756-0500

VL - 11

JO - BMC Research Notes

JF - BMC Research Notes

IS - 1

M1 - 530

ER -

Frequency and coinfection between genotypes of human papillomavirus in a population of asymptomatic women in northern Peru

Abstract

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Keywords

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