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Vacuna tetravalente de influenza en los programas nacionales de inmunización para los países de América Latina

Translated title of the contribution: Influenza tetravalent vaccines in national immunization programs for Latin-American countries
  • Alejandro E. Macías Hernández
  • , Fortino Solórzano Santos
  • , Hugo M. Aguilar Velasco
  • , María L. Ávila Agüero
  • , Fernando Bazzino Rubio
  • , Nancy C. Junqueira Bellei
  • , Pablo E. Bonvehí
  • , José Brea Del Castillo
  • , Héctor Castro Leguizamón
  • , Carla M. Allan Santos Domingues
  • , María D.L. García García
  • , Darío Londoño Trujillo
  • , Pío López Lópe
  • , Samuel Ponce De León Rosales
  • , Patricia G. Cervantes Powell
  • , Luis A.N. Suárez Ognio
  • , Guillermo M. Ruiz-Palacios y Santos
  • Universidad de Guanajuato
  • Caja Costarricense de Seguro Social
  • Hospital Infantil de Mexico Federico Gomez
  • Universidad Central del Ecuador
  • Hospital Británico
  • Universidade Federal de São Paulo
  • Centro de Educación Médica e Investigaciones Clínicas Norberto Quirno
  • Santo Domingo Institute of Technology
  • Universidad Nacional de Asunción
  • Ministério da Saúde do Brasil
  • Instituto Nacional de Salud Publica
  • Fundación Santa Fe de Bogotá
  • Hospital Universitario del Valle (Univalle)
  • Universidad Nacional Autónoma de México
  • Sanofi-Aventis
  • nstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (incmsz)

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Since 2012-2013 influenza season, World Health Organization (who) recommends the formulation of tetravalent vaccines. Globally, many countries already use tetravalent vaccines in their national immunization programs, while in Latin America only a small number. Two Influenza b lineages co-circulate, their epidemiological behavior is unpredictable. On average they represent 22.6% of influenza cases and more than 50% in predominant seasons. The lack of concordance between recommended and circulating strains was 25 and 32% in the 2010-2017 and 2000-2013 seasons, respectively. There are no clinical differences between influenza A and B. It occurs more frequently from five to 19 years of age. Influenza b has a higher proportion of attributable deaths than influenza a (1.1 vs. 0.4%), or 2.65 (95% ci 1.18-5.94). A greater number of hospitalizations when the strains mismatch (46.3 vs. 28.5%; p <.0001). Different evaluations have demonstrated its cost effectiveness. The compilation of this information supports the use of quadrivalent vaccines in Latin American countries.

Translated title of the contributionInfluenza tetravalent vaccines in national immunization programs for Latin-American countries
Original languageSpanish
Pages (from-to)92-99
Number of pages8
JournalEnfermedades Infecciosas y Microbiologia
Volume40
Issue number3
StatePublished - Jul 2020

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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