Variations in cervico-vaginal microbiota among HPV-positive and HPV-negative asymptomatic women in Peru

Hugo Carrillo-Ng; Lorena Becerra-Goicochea; Yordi Tarazona-Castro; Luis Pinillos-Vilca; Luis J. del Valle; Miguel Angel Aguilar-Luis; Carmen Tinco-Valdez; Wilmer Silva-Caso; Johanna Martins-Luna; Isaac Peña-Tuesta; Ronald Aquino-Ortega; Juana del Valle-Mendoza

doi:10.1186/s13104-020-05422-6

Variations in cervico-vaginal microbiota among HPV-positive and HPV-negative asymptomatic women in Peru

Hugo Carrillo-Ng
, Lorena Becerra-Goicochea
, Yordi Tarazona-Castro
, Luis Pinillos-Vilca
, Luis J. del Valle
, Miguel Angel Aguilar-Luis
, Carmen Tinco-Valdez
, Wilmer Silva-Caso
, Johanna Martins-Luna
, Isaac Peña-Tuesta
, Ronald Aquino-Ortega
, Juana del Valle-Mendoza

Universidad Peruana de Ciencias Aplicadas
Instituto de Investigación Nutricional
Hospital Regional Docente de Cajamarca
Facultad de Ciencias Biológicas
Universitat Politècnica de Catalunya (UPC)

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Objective: To characterize the cervicovaginal microbiota of HPV-positive and HPV-negative asymptomatic Peruvian women, by identifying the presence of 13 representative bacteria genus. Results: A total of 100 HPV-positive and 100 HPV-negative women were matched by age for comparison of microbiota. The following bacteria were more frequently identified in HPV-positive patients compared to HPV-negative: Eubacterium (68 vs 32%), Actinobacteria (46 vs 33%), Fusobacterium (11 vs 6%) and Bacteroides (20 vs 13%). A comparison between high-risk and low-risk genotypes was performed and differences were found in the detection of Actinobacteria (50 vs 33.33%), Bifidobacterium (50 vs 20.83%) and Enterococcus (50 vs 29.17%).

Original language	English
Article number	4
Journal	BMC Research Notes
Volume	14
Issue number	1
DOIs	https://doi.org/10.1186/s13104-020-05422-6
State	Published - Dec 2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Cervical cancer
HPV
Human papillomavirus
Microbiota
PCR
Peru

Access to Document

10.1186/s13104-020-05422-6

Cite this

Carrillo-Ng, H., Becerra-Goicochea, L., Tarazona-Castro, Y., Pinillos-Vilca, L., del Valle, L. J., Aguilar-Luis, M. A., Tinco-Valdez, C., Silva-Caso, W., Martins-Luna, J., Peña-Tuesta, I., Aquino-Ortega, R., & del Valle-Mendoza, J. (2021). Variations in cervico-vaginal microbiota among HPV-positive and HPV-negative asymptomatic women in Peru. BMC Research Notes, 14(1), Article 4. https://doi.org/10.1186/s13104-020-05422-6

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title = "Variations in cervico-vaginal microbiota among HPV-positive and HPV-negative asymptomatic women in Peru",

abstract = "Objective: To characterize the cervicovaginal microbiota of HPV-positive and HPV-negative asymptomatic Peruvian women, by identifying the presence of 13 representative bacteria genus. Results: A total of 100 HPV-positive and 100 HPV-negative women were matched by age for comparison of microbiota. The following bacteria were more frequently identified in HPV-positive patients compared to HPV-negative: Eubacterium (68 vs 32\%), Actinobacteria (46 vs 33\%), Fusobacterium (11 vs 6\%) and Bacteroides (20 vs 13\%). A comparison between high-risk and low-risk genotypes was performed and differences were found in the detection of Actinobacteria (50 vs 33.33\%), Bifidobacterium (50 vs 20.83\%) and Enterococcus (50 vs 29.17\%).",

keywords = "Cervical cancer, HPV, Human papillomavirus, Microbiota, PCR, Peru",

author = "Hugo Carrillo-Ng and Lorena Becerra-Goicochea and Yordi Tarazona-Castro and Luis Pinillos-Vilca and \{del Valle\}, \{Luis J.\} and Aguilar-Luis, \{Miguel Angel\} and Carmen Tinco-Valdez and Wilmer Silva-Caso and Johanna Martins-Luna and Isaac Pe{\~n}a-Tuesta and Ronald Aquino-Ortega and \{del Valle-Mendoza\}, Juana",

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doi = "10.1186/s13104-020-05422-6",

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Carrillo-Ng, H, Becerra-Goicochea, L, Tarazona-Castro, Y, Pinillos-Vilca, L, del Valle, LJ, Aguilar-Luis, MA, Tinco-Valdez, C, Silva-Caso, W, Martins-Luna, J, Peña-Tuesta, I, Aquino-Ortega, R & del Valle-Mendoza, J 2021, 'Variations in cervico-vaginal microbiota among HPV-positive and HPV-negative asymptomatic women in Peru', BMC Research Notes, vol. 14, no. 1, 4. https://doi.org/10.1186/s13104-020-05422-6

TY - JOUR

T1 - Variations in cervico-vaginal microbiota among HPV-positive and HPV-negative asymptomatic women in Peru

AU - Carrillo-Ng, Hugo

AU - Becerra-Goicochea, Lorena

AU - Tarazona-Castro, Yordi

AU - Pinillos-Vilca, Luis

AU - del Valle, Luis J.

AU - Aguilar-Luis, Miguel Angel

AU - Tinco-Valdez, Carmen

AU - Silva-Caso, Wilmer

AU - Martins-Luna, Johanna

AU - Peña-Tuesta, Isaac

AU - Aquino-Ortega, Ronald

AU - del Valle-Mendoza, Juana

PY - 2021/12

Y1 - 2021/12

N2 - Objective: To characterize the cervicovaginal microbiota of HPV-positive and HPV-negative asymptomatic Peruvian women, by identifying the presence of 13 representative bacteria genus. Results: A total of 100 HPV-positive and 100 HPV-negative women were matched by age for comparison of microbiota. The following bacteria were more frequently identified in HPV-positive patients compared to HPV-negative: Eubacterium (68 vs 32%), Actinobacteria (46 vs 33%), Fusobacterium (11 vs 6%) and Bacteroides (20 vs 13%). A comparison between high-risk and low-risk genotypes was performed and differences were found in the detection of Actinobacteria (50 vs 33.33%), Bifidobacterium (50 vs 20.83%) and Enterococcus (50 vs 29.17%).

AB - Objective: To characterize the cervicovaginal microbiota of HPV-positive and HPV-negative asymptomatic Peruvian women, by identifying the presence of 13 representative bacteria genus. Results: A total of 100 HPV-positive and 100 HPV-negative women were matched by age for comparison of microbiota. The following bacteria were more frequently identified in HPV-positive patients compared to HPV-negative: Eubacterium (68 vs 32%), Actinobacteria (46 vs 33%), Fusobacterium (11 vs 6%) and Bacteroides (20 vs 13%). A comparison between high-risk and low-risk genotypes was performed and differences were found in the detection of Actinobacteria (50 vs 33.33%), Bifidobacterium (50 vs 20.83%) and Enterococcus (50 vs 29.17%).

KW - Cervical cancer

KW - HPV

KW - Human papillomavirus

KW - Microbiota

KW - PCR

KW - Peru

UR - https://www.scopus.com/pages/publications/85098883837

U2 - 10.1186/s13104-020-05422-6

DO - 10.1186/s13104-020-05422-6

M3 - Artículo

C2 - 33407849

AN - SCOPUS:85098883837

SN - 1756-0500

VL - 14

JO - BMC Research Notes

JF - BMC Research Notes

IS - 1

M1 - 4

ER -

Variations in cervico-vaginal microbiota among HPV-positive and HPV-negative asymptomatic women in Peru

Abstract

UN SDGs

Keywords

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