TY - JOUR
T1 - Cerebral tuberculomas in AIDS patients
T2 - A forgotten diagnosis?
AU - Vidal, José E.
AU - Hernández, Adrian V.
AU - Penalva De Oliveira, Augusto C.
AU - De Souza, Alexandre
AU - Madalosso, Geraldine
AU - Da Silva, Paula R.Marques
AU - Dauar, R.
PY - 2004/9
Y1 - 2004/9
N2 - The human immunodeficiency virus (HIV) infection epidemics increased the prevalence, multi-drug resistance and disseminated forms of tuberculosis. The central nervous system (CNS) tuberculosis has high mortality and morbidity, and it is usually divided into diffuse (meningitis) and localized (tuberculoma and abscess) forms. We report three cases of cerebral tuberculomas in AIDS patients: one with definitive diagnosis, confirmed with histopathology, and two with probable diagnosis, based on clinical information, radiological images, Mycobaterium tuberculosis isolation out of the CNS and adequate response to antituberculous treatment. Further, we discuss diagnostic, therapeutic and prognostic issues of tuberculomas, with emphasis in the distinction from cerebral tuberculous abscesses. Despite of their infrequent presentation, tuberculomas should be considered in the differential diagnosis of cerebral expansive lesions in patients with AIDS.
AB - The human immunodeficiency virus (HIV) infection epidemics increased the prevalence, multi-drug resistance and disseminated forms of tuberculosis. The central nervous system (CNS) tuberculosis has high mortality and morbidity, and it is usually divided into diffuse (meningitis) and localized (tuberculoma and abscess) forms. We report three cases of cerebral tuberculomas in AIDS patients: one with definitive diagnosis, confirmed with histopathology, and two with probable diagnosis, based on clinical information, radiological images, Mycobaterium tuberculosis isolation out of the CNS and adequate response to antituberculous treatment. Further, we discuss diagnostic, therapeutic and prognostic issues of tuberculomas, with emphasis in the distinction from cerebral tuberculous abscesses. Despite of their infrequent presentation, tuberculomas should be considered in the differential diagnosis of cerebral expansive lesions in patients with AIDS.
KW - Acquired immunodeficiency syndrome
KW - Central nervous system
KW - Tuberculoma
KW - Tuberculosis
UR - https://www.scopus.com/pages/publications/5444272280
U2 - 10.1590/S0004-282X2004000500010
DO - 10.1590/S0004-282X2004000500010
M3 - Artículo
C2 - 15476071
AN - SCOPUS:5444272280
SN - 0004-282X
VL - 62
SP - 793
EP - 796
JO - Arquivos de Neuro-Psiquiatria
JF - Arquivos de Neuro-Psiquiatria
IS - 3 B
ER -
