TY - JOUR
T1 - Highly clarithromycin-resistant Helicobacter pylori infection in asymptomatic children from a rural community of Cajamarca-Peru
AU - Aguilar-Luis, Miguel Angel
AU - Palacios-Cuervo, Fernando
AU - Espinal-Reyes, Fátima
AU - Calderón-Rivera, Andrea
AU - Levy-Blitchtein, Saúl
AU - Palomares-Reyes, Carlos
AU - Silva-Caso, Wilmer
AU - Zavaleta-Gavidia, Victor
AU - Bazán-Mayra, Jorge
AU - Cornejo-Tapia, Angela
AU - Del Valle-Mendoza, Juana
AU - Del Valle, Luis J.
N1 - Publisher Copyright:
© 2018 The Author(s).
PY - 2018/11/14
Y1 - 2018/11/14
N2 - Objective: The objective of this study was to determine the prevalence of clarithromycin-resistant Helicobacter pylori in asymptomatic children in a rural community of Cajamarca (northern Peru). Results: Helicobacter pylori was detected in 17.2% (49/285) of the samples. Unboiled water consumption the most frequent associated factor in patients with positive PCR for H. pylori infection (93.9%). Clarithromycin resistant mutations were found in 79.6% (39/49) of the positive samples for H. pylori. The most frequent mutation was A2142G (46.9%), followed by the double-mutation A2142G-A2143G (28.6%).
AB - Objective: The objective of this study was to determine the prevalence of clarithromycin-resistant Helicobacter pylori in asymptomatic children in a rural community of Cajamarca (northern Peru). Results: Helicobacter pylori was detected in 17.2% (49/285) of the samples. Unboiled water consumption the most frequent associated factor in patients with positive PCR for H. pylori infection (93.9%). Clarithromycin resistant mutations were found in 79.6% (39/49) of the positive samples for H. pylori. The most frequent mutation was A2142G (46.9%), followed by the double-mutation A2142G-A2143G (28.6%).
KW - Clarithromycin
KW - Gastric disease
KW - Helicobacter pylori
KW - PCR
KW - Peptic ulcer disease
UR - https://www.scopus.com/pages/publications/85056592445
U2 - 10.1186/s13104-018-3919-z
DO - 10.1186/s13104-018-3919-z
M3 - Artículo
C2 - 30428917
AN - SCOPUS:85056592445
SN - 1756-0500
VL - 11
JO - BMC Research Notes
JF - BMC Research Notes
IS - 1
M1 - 809
ER -