TY - JOUR
T1 - Lipid accumulation product and visceral adiposity index in women with and without polycystic ovary syndrome
T2 - a systematic review and meta-analysis
AU - Ulloque-Badaracco, Juan R.
AU - Hernandez-Bustamante, Enrique A.
AU - Cabrera-Guzmán, Juan C.
AU - Delgado-Raygada, Jose E.
AU - Dotto-Vasquez, Giuseppe
AU - Maldonado-Basurto, Gian F.
AU - Figueroa-Larragán, Alberto A.
AU - Trujillo-Jurado, Katherin Z.
AU - Evaristo-Ballmann, Gustavo
AU - Flores-Gavino, Aldo
AU - Herrera-Añazco, Percy
AU - Benites-Zapata, Vicente A.
N1 - Publisher Copyright:
© The Author(s), 2025. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
PY - 2025/1/1
Y1 - 2025/1/1
N2 - Background: Polycystic ovary syndrome (PCOS) is a chronic, heterogeneous and prevalent endocrine-metabolic condition. Objectives: This study aims to synthesize the available evidence on the comparison of lipid accumulation product (LAP) and visceral adiposity index (VAI) in women with and without PCOS. Design: Systematic review and meta-analysis. Data sources and methods: A systematic search was executed across five electronic databases. Continuous variables were assessed using the standardized mean difference (SMD) and its 95% confidence interval (CI). Results: A total of 46 studies were included (n = 12,442). PCOS patients have higher values of LAP (n = 10,658; SMD: 0.65; 95% CI: 0.47–0.83, p < 0.05; I2 = 93.65%) and VAI (n = 7930; SMD: 0.53; 95% CI: 0.21–0.85; p < 0.05; I2 = 97.24%) compared to those without the syndrome. Conclusion: Women with PCOS show significantly higher VAI and LAP values than those without this syndrome.
AB - Background: Polycystic ovary syndrome (PCOS) is a chronic, heterogeneous and prevalent endocrine-metabolic condition. Objectives: This study aims to synthesize the available evidence on the comparison of lipid accumulation product (LAP) and visceral adiposity index (VAI) in women with and without PCOS. Design: Systematic review and meta-analysis. Data sources and methods: A systematic search was executed across five electronic databases. Continuous variables were assessed using the standardized mean difference (SMD) and its 95% confidence interval (CI). Results: A total of 46 studies were included (n = 12,442). PCOS patients have higher values of LAP (n = 10,658; SMD: 0.65; 95% CI: 0.47–0.83, p < 0.05; I2 = 93.65%) and VAI (n = 7930; SMD: 0.53; 95% CI: 0.21–0.85; p < 0.05; I2 = 97.24%) compared to those without the syndrome. Conclusion: Women with PCOS show significantly higher VAI and LAP values than those without this syndrome.
KW - adiposity
KW - lipid accumulation product
KW - meta-analysis
KW - polycystic ovary syndrome
KW - systematic review
KW - visceral adiposity index
UR - https://www.scopus.com/pages/publications/105022596797
U2 - 10.1177/20420188251397203
DO - 10.1177/20420188251397203
M3 - Artículo
AN - SCOPUS:105022596797
SN - 2042-0188
VL - 16
JO - Therapeutic Advances in Endocrinology and Metabolism
JF - Therapeutic Advances in Endocrinology and Metabolism
ER -
