Prompt Initiation of Maternal Antiretroviral Therapy After HIV Seroconversion in Pregnancy Effectively Prevents Vertical Transmission and Other Adverse Infant Outcomes

Kavya G. Sundar; Lanbo Z. Yang; Mary C. Cambou; Ivana R.S. Varella; Marineide G. Melo; Eddy R. Segura; Ângela P. Ziegler; Breno R. Santos; Karin Nielsen-Saines

doi:10.1097/INF.0000000000004562

Prompt Initiation of Maternal Antiretroviral Therapy After HIV Seroconversion in Pregnancy Effectively Prevents Vertical Transmission and Other Adverse Infant Outcomes

Kavya G. Sundar
, Lanbo Z. Yang
, Mary C. Cambou
, Ivana R.S. Varella
, Marineide G. Melo
, Eddy R. Segura
, Ângela P. Ziegler
, Breno R. Santos
, Karin Nielsen-Saines

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

1 Cita (Scopus)

Resumen

From January 2008 to December 2018, 1348 HIV-exposed infants were born in Porto Alegre, Brazil; 18.8% had adverse infant outcomes (AIO) including vertical transmission (1.9%), stillbirth/neonatal death (4.0%) and loss to follow-up before HIV diagnosis (12.9%). Timing of maternal HIV diagnosis was not associated with AIO but absent antiretroviral therapy use was. Lack of maternal antiretroviral therapy use is a significant risk factor for AIO.

Idioma original	Inglés
Páginas (desde-hasta)	40-43
Número de páginas	4
Publicación	Pediatric Infectious Disease Journal
Volumen	44
N.º	1
DOI	https://doi.org/10.1097/INF.0000000000004562
Estado	Publicada - 1 ene. 2025
Publicado de forma externa	Sí

ODS de las Naciones Unidas

Este resultado contribuye a los siguientes Objetivos de Desarrollo Sostenible

Acceder al documento

10.1097/INF.0000000000004562

Otros archivos y enlaces

Enlace a la publicación en Scopus

Citar esto

Sundar, K. G., Yang, L. Z., Cambou, M. C., Varella, I. R. S., Melo, M. G., Segura, E. R., Ziegler, Â. P., Santos, B. R., & Nielsen-Saines, K. (2025). Prompt Initiation of Maternal Antiretroviral Therapy After HIV Seroconversion in Pregnancy Effectively Prevents Vertical Transmission and Other Adverse Infant Outcomes. Pediatric Infectious Disease Journal, 44(1), 40-43. https://doi.org/10.1097/INF.0000000000004562

@article{efaa8b36c0ab44dbb01550c74b8a2d54,

title = "Prompt Initiation of Maternal Antiretroviral Therapy After HIV Seroconversion in Pregnancy Effectively Prevents Vertical Transmission and Other Adverse Infant Outcomes",

abstract = "From January 2008 to December 2018, 1348 HIV-exposed infants were born in Porto Alegre, Brazil; 18.8\% had adverse infant outcomes (AIO) including vertical transmission (1.9\%), stillbirth/neonatal death (4.0\%) and loss to follow-up before HIV diagnosis (12.9\%). Timing of maternal HIV diagnosis was not associated with AIO but absent antiretroviral therapy use was. Lack of maternal antiretroviral therapy use is a significant risk factor for AIO.",

keywords = "HIV in pregnancy, HIV vertical transmission, adverse infant outcomes, antiretroviral therapy in pregnancy, maternal HIV seroconversion",

author = "Sundar, \{Kavya G.\} and Yang, \{Lanbo Z.\} and Cambou, \{Mary C.\} and Varella, \{Ivana R.S.\} and Melo, \{Marineide G.\} and Segura, \{Eddy R.\} and Ziegler, \{{\^A}ngela P.\} and Santos, \{Breno R.\} and Karin Nielsen-Saines",

year = "2025",

month = jan,

day = "1",

doi = "10.1097/INF.0000000000004562",

language = "Ingl{\'e}s",

volume = "44",

pages = "40--43",

journal = "Pediatric Infectious Disease Journal",

issn = "0891-3668",

publisher = "Lippincott Williams and Wilkins",

number = "1",

}

Sundar, KG, Yang, LZ, Cambou, MC, Varella, IRS, Melo, MG, Segura, ER, Ziegler, ÂP, Santos, BR & Nielsen-Saines, K 2025, 'Prompt Initiation of Maternal Antiretroviral Therapy After HIV Seroconversion in Pregnancy Effectively Prevents Vertical Transmission and Other Adverse Infant Outcomes', Pediatric Infectious Disease Journal, vol. 44, n.º 1, pp. 40-43. https://doi.org/10.1097/INF.0000000000004562

Prompt Initiation of Maternal Antiretroviral Therapy After HIV Seroconversion in Pregnancy Effectively Prevents Vertical Transmission and Other Adverse Infant Outcomes. / Sundar, Kavya G.; Yang, Lanbo Z.; Cambou, Mary C. et al.
En: Pediatric Infectious Disease Journal, Vol. 44, N.º 1, 01.01.2025, p. 40-43.

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

TY - JOUR

T1 - Prompt Initiation of Maternal Antiretroviral Therapy After HIV Seroconversion in Pregnancy Effectively Prevents Vertical Transmission and Other Adverse Infant Outcomes

AU - Sundar, Kavya G.

AU - Yang, Lanbo Z.

AU - Cambou, Mary C.

AU - Varella, Ivana R.S.

AU - Melo, Marineide G.

AU - Segura, Eddy R.

AU - Ziegler, Ângela P.

AU - Santos, Breno R.

AU - Nielsen-Saines, Karin

PY - 2025/1/1

Y1 - 2025/1/1

N2 - From January 2008 to December 2018, 1348 HIV-exposed infants were born in Porto Alegre, Brazil; 18.8% had adverse infant outcomes (AIO) including vertical transmission (1.9%), stillbirth/neonatal death (4.0%) and loss to follow-up before HIV diagnosis (12.9%). Timing of maternal HIV diagnosis was not associated with AIO but absent antiretroviral therapy use was. Lack of maternal antiretroviral therapy use is a significant risk factor for AIO.

AB - From January 2008 to December 2018, 1348 HIV-exposed infants were born in Porto Alegre, Brazil; 18.8% had adverse infant outcomes (AIO) including vertical transmission (1.9%), stillbirth/neonatal death (4.0%) and loss to follow-up before HIV diagnosis (12.9%). Timing of maternal HIV diagnosis was not associated with AIO but absent antiretroviral therapy use was. Lack of maternal antiretroviral therapy use is a significant risk factor for AIO.

KW - HIV in pregnancy

KW - HIV vertical transmission

KW - adverse infant outcomes

KW - antiretroviral therapy in pregnancy

KW - maternal HIV seroconversion

UR - https://www.scopus.com/pages/publications/85207156795

U2 - 10.1097/INF.0000000000004562

DO - 10.1097/INF.0000000000004562

M3 - Artículo

AN - SCOPUS:85207156795

SN - 0891-3668

VL - 44

SP - 40

EP - 43

JO - Pediatric Infectious Disease Journal

JF - Pediatric Infectious Disease Journal

IS - 1

ER -

Prompt Initiation of Maternal Antiretroviral Therapy After HIV Seroconversion in Pregnancy Effectively Prevents Vertical Transmission and Other Adverse Infant Outcomes

Resumen

ODS de las Naciones Unidas

Acceder al documento

Otros archivos y enlaces

Huella

Citar esto