TY - JOUR
T1 - Variations in cervico-vaginal microbiota among HPV-positive and HPV-negative asymptomatic women in Peru
AU - Carrillo-Ng, Hugo
AU - Becerra-Goicochea, Lorena
AU - Tarazona-Castro, Yordi
AU - Pinillos-Vilca, Luis
AU - del Valle, Luis J.
AU - Aguilar-Luis, Miguel Angel
AU - Tinco-Valdez, Carmen
AU - Silva-Caso, Wilmer
AU - Martins-Luna, Johanna
AU - Peña-Tuesta, Isaac
AU - Aquino-Ortega, Ronald
AU - del Valle-Mendoza, Juana
N1 - Publisher Copyright:
© 2020, The Author(s).
PY - 2021/12
Y1 - 2021/12
N2 - Objective: To characterize the cervicovaginal microbiota of HPV-positive and HPV-negative asymptomatic Peruvian women, by identifying the presence of 13 representative bacteria genus. Results: A total of 100 HPV-positive and 100 HPV-negative women were matched by age for comparison of microbiota. The following bacteria were more frequently identified in HPV-positive patients compared to HPV-negative: Eubacterium (68 vs 32%), Actinobacteria (46 vs 33%), Fusobacterium (11 vs 6%) and Bacteroides (20 vs 13%). A comparison between high-risk and low-risk genotypes was performed and differences were found in the detection of Actinobacteria (50 vs 33.33%), Bifidobacterium (50 vs 20.83%) and Enterococcus (50 vs 29.17%).
AB - Objective: To characterize the cervicovaginal microbiota of HPV-positive and HPV-negative asymptomatic Peruvian women, by identifying the presence of 13 representative bacteria genus. Results: A total of 100 HPV-positive and 100 HPV-negative women were matched by age for comparison of microbiota. The following bacteria were more frequently identified in HPV-positive patients compared to HPV-negative: Eubacterium (68 vs 32%), Actinobacteria (46 vs 33%), Fusobacterium (11 vs 6%) and Bacteroides (20 vs 13%). A comparison between high-risk and low-risk genotypes was performed and differences were found in the detection of Actinobacteria (50 vs 33.33%), Bifidobacterium (50 vs 20.83%) and Enterococcus (50 vs 29.17%).
KW - Cervical cancer
KW - HPV
KW - Human papillomavirus
KW - Microbiota
KW - PCR
KW - Peru
UR - https://www.scopus.com/pages/publications/85098883837
U2 - 10.1186/s13104-020-05422-6
DO - 10.1186/s13104-020-05422-6
M3 - Artículo
C2 - 33407849
AN - SCOPUS:85098883837
SN - 1756-0500
VL - 14
JO - BMC Research Notes
JF - BMC Research Notes
IS - 1
M1 - 4
ER -
